Endocrine Abstracts

The transformation of toxic nodular goitre into autoimmune hyperthyroidism with development of thyrotropin receptor antibodies (TSHRAb) as effect of 131I therapy is rarely investigated.The aim of the study is to present cases of patients with toxic nodular goitre who developed autoimmune hyperthyroidism after initial 131I dose, and results of treatment with second 131I dose or thyrostatics.Four pati...

Aim: The aim of the study was the evaluation of the TSHRAb level changes and the comparison with thyroid function in patients with Graves’ disease treated with 131I 10 years ago.Material and methods: The study has been conducted in 67 patients (57 women, 10 men) aged 27–72 y (mean 48 years) with Graves’ disease.All patients were treated with 131I due to hyperthyroidism confirmed by fT3, fT4 and ...

Introduction: Hyperthyroidism is one of frequently encountered clinical syndromes appearing in about 2% of adult population. The aim of this study was to evaluate the efficacy of radioiodine treatment in relation to the form of hyperthyroidism.Material and methods: The study investigated 300 patients: 150 with Graves’ disease and 150 with a toxic adenoma goiter (109 with a solitary nodule and 41 with a multinodular goiter). In all the cases, the est...

Aim: The aim of the study was to evaluate the relationship between TSHAb levels and thyroid function and size in patients with Graves’ disease and then to estimate the influence of TSHAb on the outcome of 131I therapy.Material and methods: Two hundred and one patients (168 females and 33 males, mean age 47.76 years, range 18–84) with Graves’ disease were enrolled. Before therapy, plasma fT3, fT4, TSH (DELFI...